The five-year TRACK Tuberculosis (TRACK-TB) activity aimed to increase detection of TB cases and improve treatment success rates to meet national targets for reducing TB, multidrug-resistant TB (MDR-TB), and TB/HIV co-infection. The project, which began in 2013, worked with the Government of Uganda to enhance the National Tuberculosis and Leprosy Programme (NTLP)’s ability to plan, monitor, and implement TB control activities. The TRACK TB team worked to improve MDR-TB management, as well as urban- and community-based TB treatment strategies based on the World Health Organization’s directly observed treatment, short course (DOTS) model. TRACK TB implemented activities in the capital, Kampala, and provided technical assistance to district-based USAID-funded partners in Uganda’s four regions: Eastern, Central Eastern, South Western, and Mid-North. The project worked to support the programmatic management of MDR-TB at the NTLP central unit and at six treatment sites and 72 health facilities in and around Kampala.