Antiretroviral Treatment as Prevention: Opportunities and Challenges


Treatment as Prevention (TasP) describes HIV prevention methods that use antiretroviral therapy (ART) in both HIV-positive and HIV-negative persons to decrease the risk of HIV transmission. This technical brief covers: (1) The rationale for TasP; (2) New thoughts on using ART in HIV negative people to protect against infection; (3) Current WHO global policy guidance and current practices in the Southern African region; and (4) Recommendations for consideration.

This technical brief is part of a series of briefs on priority HIV prevention topics developed by MSH’s Building Local Capacity for Delivery of HIV Services in Southern Africa Project (the BLC Project) and the Southern African Development Community. They were written based on insights gained from a review of the HIV prevention literature commissioned by the BLC Project in 2011, scientific developments presented at the XIX International AIDS Conference in July 2012, as well as recent World Health Organization (WHO) and UNAIDS publications.