Prevention of Mother to Child Transmission of HIV


This technical brief summarizes the latest evidence on PMTCT of HIV in the Southern African region. It presents the current WHO guidance on antiretroviral use in pregnant HIV-positive women: Options A, B and B+. Option B+ is a new development, emerging from experiences in Malawi, which was the focus of much attention at the recent International AIDS Conference. It describes regional guidance from the Southern African Development Community, and highlights recommendations and promising practices in the region.

This technical brief is part of a series of briefs on priority HIV prevention topics developed by MSH’s Building Local Capacity for Delivery of HIV Services in Southern Africa Project (the BLC Project) and the Southern African Development Community. They were written based on insights gained from a review of the HIV prevention literature commissioned by the BLC Project in 2011, scientific developments presented at the XIX International AIDS Conference in July 2012, as well as recent World Health Organization (WHO) and UNAIDS publications.