Built on Commitment. Driven by Results: MSH’s 2025 Annual Report

For 55 years, MSH has worked alongside governments and partners to strengthen the systems that make better health possible. Today, we are building on that foundation for what comes next—combining deep implementation experience with stronger advisory capabilities to help countries strengthen institutions, mobilize resources, use evidence, and sustain progress over time.

Our latest Annual Report reflects the results these partnerships are delivering today and how MSH is evolving to meet the opportunities and demands ahead.

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Dear Colleagues,

The past year fundamentally tested the global health sector. Development assistance fell sharply as major funders realigned or withdrew support, placing increased pressure on governments already operating within significant fiscal constraints. Leaders were suddenly asked to do far more with far less while remaining fully accountable for the health of their populations.

MSH has not been immune to the same forces reshaping the global health landscape. We have made deliberate choices to adapt—refining how we operate, how we partner, and where we focus—so we can continue standing alongside governments at a time when that partnership matters most. We have emerged smaller and more agile, clearer and more audacious about the role we are uniquely positioned to play.

As part of that evolution, we have expanded our advisory capabilities in financing, governance, institutional strengthening, and systems transformation, while continuing the deep technical engagement and implementation support that remain central to who we are. Together, these capabilities help governments align priorities, mobilize resources, strengthen institutions, and turn strategy into sustainable action.

Importantly, these shifts have not changed our strategic direction; they have reinforced it. The strategy we defined for 2023–2030 remains aligned with the realities countries are navigating today: strengthening locally led systems, mobilizing sustainable financing, advancing equity, supporting evidence-based decision-making, and enabling governments to lead lasting change.

For 55 years, MSH has worked alongside governments to strengthen the systems that deliver health care: the workforces, supply chains, financing mechanisms, and governance structures that make consistent, quality care possible. The expertise, relationships, and operational experience we have built over decades are precisely what this moment demands, and we are ready to meet it—guided, as we have always been, by the belief that everyone, everywhere, deserves the opportunity for a healthy life.

Read the full letter in the Annual Report

Thank you for standing with us.

**Marian W. Wentworth**, *President and Chief Executive Officer*

John Isaacson, MSH Chair of the Board of Directors

JI Signature — John Isaacson, Chair of the Board of Directors

MSH’s 2025 Annual Report

Explore how MSH and our partners are strengthening health systems, adapting to a changing global environment, and building the capabilities countries need to sustain progress.

Read the Annual Report

View 2025 Financial Data

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The expertise, relationships, and operational experience we have built over decades are precisely what this moment demands.

A group of people sitting at the table during a meeting

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Through a partnership with the Mastercard Foundation, MSH Nigeria is working with national and state governments to reskill and upskill 44,000 community health workers across 17 states—while strengthening the institutions, digital systems, and government structures needed to support their performance over time.

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MSH-led modeling found that sustained investment in malaria could generate $231 billion in economic gains across Africa by 2030—helping demonstrate that health spending is not only a social investment, but an economic one.

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For decades, MSH’s leadership development approaches have helped leaders strengthen problem-solving, teamwork, accountability, and results-driven management across health systems in more than 80 countries. Today, MSH continues to adapt and expand these approaches to meet evolving health system priorities.

Trucks en route to conflict affected areas in Amhara region carrying lifesaving supplies

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In the final quarter of 2025, MSH supported efforts to enable delivery of $8.7 million in HIV, tuberculosis, malaria, and maternal health commodities to nearly 1,000 health facilities and offices across conflict-affected regions, supporting treatment and care for more than 1.3 million Ethiopian people.

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In Afghanistan, nearly 700 health workers participated in more than 10,000 learning sessions focused on maternal and newborn care—strengthening clinical skills, continuous learning, and facility-led quality improvement.

Annual Reports

Read the stories of the people with whom we work. Together, with our diverse funding and implementing partners, we work with local health leaders and institutions around the world to create lasting health impact.