For more than eight years, the Supply Chain Management System (SCMS) has been saving lives through stronger supply chains. Funded by the US President’s Emergency Plan for AIDS Relief (PEPFAR), SCMS is supporting rapid scale-up of HIV/AIDS programs, creating a reliable global supply chain where none existed, leveraging economies of scale to reduce costs, and serving as an emergency provider of choice for AIDS programs. SCMS is managed by the non-profit Partnership for Supply Chain Management (PFSCM)—a partnership of John Snow, Inc. (JSI), and Management Sciences for Health (MSH).